371: What Founders Still Get Wrong in Crypto with Guest speaker William Quigley from WAX + Tether
22 March 2026

371: What Founders Still Get Wrong in Crypto with Guest speaker William Quigley from WAX + Tether

Web3 with Sam Kamani

About

In this episode, I sit down with William Quigley, co-founder of WAX and co-founder of Tether. We go deep into what is actually happening in crypto right now. We talk about stablecoins, gaming, startup strategy, market cycles, and why founders need insight more than hype. William shares hard-earned lessons from building early crypto products and explains where real value may come from next.

This is a must-listen for founders, builders, and anyone trying to understand where Web3 is heading. We unpack why stablecoins matter, why most internal innovation fails, why altcoin speculation looks weaker this cycle, and what kinds of businesses still have a real shot at winning.

Key points

    00:00 — Intro to the episode and why this conversation matters for founders

    01:24 — William’s path into crypto through virtual item trading in gaming

    04:23 — Why gaming platforms resist asset portability and user ownership

    05:26 — Why blockchain gaming adoption has been slower than expected

    07:26 — Prediction markets, speculation, and why they are still niche

    10:31 — How Tether started and the problem stablecoins were built to solve

    13:28 — Why Tether’s model worked and why algorithmic stablecoins failed

    17:07 — The future of stablecoins and the three models William sees winning

    20:30 — Will non-USD stablecoins grow over time?

    23:35 — Why FX fees are massive and how stablecoins can reduce that pain

    27:06 — What recent crypto events reveal about institutional vs retail interest

    29:14 — Why this cycle feels different and why altcoin season never fully arrived

    34:32 — Sam’s view on AI helping chains build actual apps, not just more infra

    37:42 — Why most internal innovation fails without real market insight

    44:28 — How to think about fear, greed, and crypto sentiment

    46:38 — If William started again today, what kind of business would he build?

    50:26 — Sam on AI, quantum computing, and selling tools in the next tech wave

    54:22 — Why timing matters as much as the idea itself

    56:09 — Institutional capital, long-term adoption, and what may come next

Disclaimer

Nothing mentioned in this podcast is investment advice and please do your own research.


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