Immune

The Immune team discusses the groundbreaking discoveries of regulatory T cells, which was the topic of the 2025 Nobel Prize in Physiology or Medicine. Hosts: Vincent Racaniello, Cindy Leifer, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Sakaguchi lab paper on FoxP3 and regulatory T cells (Science 2003)...

Susan Schwab talks about how she got the research bug, bugs she ate, and her research on how the lipid S1P helps T cells decide- should I stay or should I go. Host: Cindy Leifer Guest: Susan Schwab Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Schwab lab website Monocytes produce the lipid S1P to regulate T cell movement...

Immune discusses cross-reactive antibodies to avian influenza neuraminidases and a role for gut-derived T cells in the brain to regulate eating behavior. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Antibody cross-reactivity to influenza H5N1 (Cell...

Kristian Andersen from Scripps Research Institute joins Cindy to talk about how he got interested in virus evolution, how the immune system drives viral adaptation, and what we can learn from this research to better prepare us for the next pandemic. Host: Cindy Leifer Guest: Kristian Andersen Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV...

Cindy and Steph discuss a paper that challenges the textbook dogma that B cells must first bind to an antigen for antibody affinity maturation to occur, and a snippet on dysfunctional T cells during bacterial vaginosis. Hosts: Cindy Leifer and Steph Langel Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Somatic hypermutation...

Cindy sits down with Bali Pulendran at the AAI 2025 meeting where he told the story of how a childhood fascination with the cosmos grew into a career addressing fundamental questions about the human immune response, and how when an antigen enters the body it is like the big bang in how it initiates immune responses. Host: Cindy Leifer Guest: Bali Pulendran Subscribe (free): Apple Podcasts, RSS,...

Elizabeth Marnik, also known as Science Whiz Liz, grew up unvaccinated, yet she is now an immunologist, science communicator, and advocate for vaccines–this is her story. Host: Cindy Leifer Guest: Elizabeth Marnick Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server More about Liz on her webpage ScienceWhizLiz on Instagram From...

Immune discusses the potential future of delivering vaccines by flossing your teeth and how antibodies in human milk shape the normal immune responses in newborns. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server Floss-based vaccination (Nat Biomed...

Cindy speaks with Aimee Pugh Bernard from University of Colorado about her career and her passion for teaching and communicating immunology to the public. Host: Cindy Leifer Guest: Aimee Pugh Bernard Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord Server More about Aimee on her webpage Funsizeimmuninja on Instagram Fun Size Science...

Immune discusses how cancer cells swap mitochondria with T cells and then digs in for a discussion of an unusual checkpoint blockade that failed for cancer but could be repurposed for autoimmune inflammation. Hosts: Vincent Racaniello, Cindy Leifer, Steph Langel, and Brianne Barker Subscribe (free): Apple Podcasts, RSS, email Become a patron of Immune! Links for this episode MicrobeTV Discord...