Linking Obesity to Alzheimer’s: The Lipid Signals Driving Neurodegeneration
31 October 2025

Linking Obesity to Alzheimer’s: The Lipid Signals Driving Neurodegeneration

Clinician's Roundtable

About
Guest: Stephen Wong, PhD




Emerging research suggests that the effects of obesity extend beyond metabolism, reaching the brain in ways that may influence the development of Alzheimer’s disease. Tune in as Dr. Stephen Wong discusses how fat-derived vesicles act as molecular messengers, potentially linking systemic inflammation and lipid imbalance to neurodegenerative changes. Dr. Wong is the John S. Dunn Presidential Distinguished Chair in Biomedical Engineering at Houston Methodist Hospital and Associate Director at Houston Methodist Cancer Center. He’s also a Professor of Radiology, Neurosciences, Pathology, and Laboratory Medicine at Weill Cornell Medicine.