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ADME UP: A COMPREHENSIVE REVIEW OF PHARMACOKINETIC CONCEPTS (PREMIUM) │ EP118
09 October 2026

ADME UP: A COMPREHENSIVE REVIEW OF PHARMACOKINETIC CONCEPTS (PREMIUM) │ EP118

Atomic Anesthesia

About

In this premium episode, we’re breaking down pharmacokinetics, the concepts that explain what happens to a drug after it enters the body. From distribution and protein binding to metabolism, clearance, and context-sensitive half-time, we’ll connect the equations and terminology to how anesthetic drugs actually behave in the OR and focus on the high-yield concepts you need to know for the SEE/NCE.

In this episode:

    Volume of distribution, protein binding, and drug distributionClearance, elimination, and half-lifeFirst-order vs. zero-order kineticsHepatic extraction ratio and factors that affect drug metabolismContext-sensitive half-time and continuous infusionsHigh-yield pharmacokinetic concepts for the SEE/NCE

This episode is part of our 12-week SEE/NCE podcast series, designed to follow the Atomic Anesthesia SEE/NCE Study Plan week by week.

Want to study along with the episode? Join the Atomic Anesthesia learning platform to get the accompanying worksheet, plus access to our members-only podcast episodes and additional SEE/NCE study resources.

FREE RESOURCE FOR THIS EPISODE:

SEE/NCE Study Plan — A structured, week-by-week plan to pass your boards. Head to atomicanesthesia.com/freebies/see-nce-study-plan to grab it free.

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